Leading the way in oligonucleotide bioanalysis and quantification

Oligonucleotides are exploding as a therapeutic modality. The ability of oligonucleotide therapies to modulate disease mechanisms at the mRNA level opens up the potential to treat pathologies previously considered “undruggable”.

The molecular properties of oligonucleotides place them somewhere between small molecules and protein therapeutics. SCIEX recognizes the special analytical challenges that oligonucleotide therapeutics present to scientists. We have partnered with scientists in the pharmaceutical and biopharmaceutical industries to develop precise, sensitive and efficient analytical solutions to enable your IND or NDA seeking programs.

Our market-leading negative-ion performance across our mass spectrometry portfolio delivers extreme sensitivity for your most challenging therapeutic oligonucleotides. You will not only see a boost in sensitivity with microflow chromatography, but also a decrease in system contamination and downtime for cleaning. Confidently run your analyses with the ease of connecting SCIEX sources and employing instrumentation designed specifically for microflow.