知识库文章

Diagnosing signal instability when processing data in Analyst®, MultiQuant™, or SCIEX OS software

Signal instability typically results in fluctuating responses from samples with the same level of analytes, causing significant variability in measured outcomes. Due to random fluctuations in peak area, signal instability could also affect linearity and recovery. If signal instability is observed while processing data in Analyst®, MultiQuant, or SCIEX OS software, it's possible to diagnose the source of signal instability by evaluating: 1) sample and material preparation, 2) LCMS method instability, and 3) instrument issues.